A. Gaskell, R.D. Sanders, J. Sleigh

British Journal of Anaesthesia, Vol. 121, Issue 1, p327–329
Published online: May 8, 2018

Editor—Brown and colleagues1 have apparently misquoted our original conclusions.2 We concluded that an alpha-delta dominant frontal EEG power spectrum is not sufficient to ensure unconsciousness during intended general anaesthesia.2 It is hard to argue against the validity of our conclusion, given that three of the six observed volitional responses occurred during periods where the frontal EEG showed a clear alpha-delta dominant pattern. With regards to an EEG marker of phase-amplitude coupling (PmaxI), we concluded that frontal EEG parameters do not readily discriminate volitional responsiveness from unresponsiveness.